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Merck Research Scientist - Cellular Pharmacology in Boston, Massachusetts

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

The Cell Pharmacology group in the Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in immunology, oncology or cardiometabolic cellular assays to join our Research Laboratories in Boston. The primary tasks of the successful candidate will be to develop and characterize high throughput in vitro and ex vivo cell-based assays to support autoimmune, cancer, or cardiometabolic projects. These high throughput cell assays will use both cell lines and primary human cells.

Responsibilities:

  • Characterize and optimize in vitro and ex vivo assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.

  • Evaluate the pharmacology of novel molecules, peptides, antibodies and other modalities for therapeutic potential in immunology, oncology or cardiometabolic indications.

  • Potential involvement in ex vivo translational model establishment.

  • Maintain timely, accurate laboratory records of activities & comply with good documentation practices.

  • Effectively partner with integrated teams in a matrix organizational setting to contribute to the conduct of studies and to the success of discovery programs.

Required Education & Experience:

  • B.S./B.A. degree with a minimum 3 years of experience; or a M.S. degree with a minimum 1 year of experience.

  • Proficiency in cell culture, passaging and harvesting is required.

  • Candidate should be a strong team player with excellent oral and written communication skills.

Preferred Experience:

  • Prior experience with primary human cells is desired.

  • Experience in the selection, optimization and characterization of effective immunology, oncology, or cardiometabolic assays is desired.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

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Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

OEB4

Job Posting End Date:

07/10/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date: 07/10/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R301002

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