Job Information
Merck Senior Scientist, Cytometric Profiling in South San Francisco, California
Job Description
We are seeking an experienced and enthusiastic scientist to join the Cytometric Profiling group at our company's Research Laboratories in South San Francisco. This is a full-time position that requires on-site, laboratory-based work. Candidates should have extensive expertise in flow cytometry panel design, staining, sample acquisition, and data analysis. We have a large fleet of instruments including LSR Fortessas (BD Biosciences), CytoFLEXs (Beckman Coulter), and Auroras (Cytek Biosciences). The successful candidate will have good working knowledge of the hardware, fluidics, and optics involved with flow cytometry, and should be able to troubleshoot common issues. Experience with cell sorting, particularly on Aria Fusion cell sorters (BD Biosciences), is required. In this role, the candidate will be performing the daily instrument startup, QC, and shutdown procedures, as well as helping manage routine instrument maintenance and troubleshooting.
In addition to the FACS Lab responsibilities, the candidate will also support oncology and immunology discovery projects typically involving the profiling of various human, non-human primate, or murine tissues by flow cytometry and/or cell sorting. The successful candidate will work with program team members as well as with other departments to contribute to the preclinical development of novel therapeutics headed to the clinic.
This position requires a candidate who has excellent communication skills and who will enjoy working with a large, diverse group of scientists. The successful candidate will be willing to help both experienced and new users when assistance is needed.
Education Requirements:
Either BS (and 6+ years of industry/relevant academic experience) or MS (and 3+ years of industry/relevant academic experience) in Biology or relevant discipline
PhD in Biology, Immunology, or relevant discipline plus 0-3+ years of industry or postdoctoral experience
Required Experience and Skills:
Experience with Flow Cytometry, preferably with BD Biosciences or Beckman Coulter flow cytometers
Experience with Cell Sorting (FACS), preferably with BD Biosciences cell sorters
Proficiency with FlowJo data analysis software
Excellent communication and interpersonal skills
Proficiency with MS Office applications on the Windows operating system
Must be able to lift a 20-Liter box of sheath fluid (45 lbs. each)
Preferred Experience and Skills:
Expertise in Spectral Cytometry, preferably with Cytek Biosciences spectral cytometers
Immunology background
Biomarker discovery experience
Cell preparation for single cell RNA-sequencing
Single cell RNA-sequencing using the 10X Genomics platform
Proficiency with high-dimensional data clustering and analytical methods
Proficiency with TIBCO Spotfire, GraphPad Prism, OMIQ
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
Under New York State, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.
Expected salary range:
$125,000.00 - $196,800.00
Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here (https://www.benefitsatmerck.com/) .
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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic/International
VISA Sponsorship:
Yes
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
BSL2 laboratory
Job Posting End Date:
05/19/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Job Posting End Date: 05/19/2024
A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Requisition ID: R292751